Created by bacteria that do not allow its owner to gain weight




Adding food experimental mice genetically modified version of E. coli, which normally lives in the gastrointestinal tract of a human or animal, helped researchers from rodents rid of excess weight. It turns out that this is possible without surgery.

According Popsci, microorganisms were adjusted so as to synthesize a substance called NAPE (N-acylphosphatidylethanolamine), which the body converts to a hormone produced in the process of digestion. This hormone is then passed into the brain through the blood and reduces appetite. The idea is that the bacterium causes mice to think that they eat more than they really are.

In a study published in the scientific journal The Journal of Clinical Investigation, rodents, which added bacteria in drinking water, and a control group of rodents fed a high-calorie food. The mice who ate the bacteria decreased appetite, weight gain, they stopped and began to show a lower insulin resistance. Effect lasted about four weeks.

Scientists believe that these bacteria can use probiotics for human consumption. If the drug would be effective and safe, it will give a great head start existing drugs against obesity. Advantage on the basis of probiotic E. coli and that the gut is a natural place of its habitat. Other micro-organisms do not colonize the human gut as well as the bacterium .
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