Scientists have found a way to reduce the risk of rejection of new organs transplant




Scientists have found a way to reduce the risk of rejection of new organs transplant


No matter how far medicine has advanced and how well transplant operations are needed to man the new bodies. The problem is that often the transplanted organs simply alienated from the human body. Deeply thinking on that issue, the scientists from the University of Washington have created special synthetic biomaterial, which they claim eliminates the risk of rejection of transplanted tissue by the immune system.

Most often in such cases the new transplanted organ is perceived by the human body as a foreign object. The immune system is trying to isolate the foreign body and it creates around it with a thick layer of collagen (connective tissue). So often that, for example, an artificial heart valve or electrode body is blocked and literally could not function properly.

A group of researchers led by Buddy Ratner and Shaoyi Jiang have developed special Hydrogel implant to become visible to the immune system. This consists of a special polymer gel with positive and negative charge that literally makes a protein (collagen in this case) its cover and thus isolate.

In laboratory tests, this Hydrogel was tested on mice. Three months after transplant grafts around them do not have any collagen capsules. In the case of a human organism, collagen capsules usually can form in the first few weeks after planting. If during this time, they did not begin to be formed, then the exclusion is likely already and will not start.

“Scientists have repeatedly tried to find a suitable material for this purpose, but this is probably the first case of successful use of non-porous synthetic substances that can protect the implant from forming around the collagen capsules. All this will subsequently increase the probability of successful transplanting artificial organs and specialized medical devices, “said Dr Jiang.

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Tags: Hydrogel, Medicine, organ transplantation.


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